Uptake of technetium-99m hexamethylpropylene amine oxime labelled white cells in lymph nodes involved in non-Hodgkin's lymphoma
Identifieur interne : 000077 ( Main/Exploration ); précédent : 000076; suivant : 000078Uptake of technetium-99m hexamethylpropylene amine oxime labelled white cells in lymph nodes involved in non-Hodgkin's lymphoma
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Abstract
Radiolabelled white cell scanning is widely used to detect the presence of infection. We present a case of non-Hodgkin's lymphoma manifesting with signs and symptoms suggestive of infection, in which a technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) white cell scan demonstrated high uptake in lymph nodes involved by lymphoma. Differential cell analysis showed preferential lymphocyte labelling. The classification and management of the disease were changed accordingly. Our findings suggest that a future role for99mTc-HMPAO labelled white cells in the assessment of disease activity of lymphoma should be investigated.
DOI: 10.1007/BF01791154
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Hammersley</name><affiliation wicri:level="1"><mods:affiliation>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey</wicri:regionArea><wicri:noRegion>Surrey</wicri:noRegion></affiliation></author><author><name>V. Ralph McCready</name><affiliation wicri:level="1"><mods:affiliation>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey</wicri:regionArea><wicri:noRegion>Surrey</wicri:noRegion></affiliation></author><author><name>Alan H. Horwich</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Oncology, The Royal Marsden Hospital, Surrey, UK</mods:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Oncology, The Royal Marsden Hospital, Surrey</wicri:regionArea><wicri:noRegion>Surrey</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="RBID">ISTEX:259_1995_Article_BF01791154.pdf</idno><date when="1995">1995</date><idno type="doi">10.1007/BF01791154</idno><idno type="wicri:Area/Main/Corpus">000B18</idno><idno type="wicri:Area/Main/Curation">000B18</idno><idno type="wicri:Area/Main/Exploration">000077</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Indium-111</term><term>Lymphoma</term><term>Technetium-99m hexamethylpropylene amine oxime</term><term>White blood cell labelling</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="eng">Radiolabelled white cell scanning is widely used to detect the presence of infection. We present a case of non-Hodgkin's lymphoma manifesting with signs and symptoms suggestive of infection, in which a technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) white cell scan demonstrated high uptake in lymph nodes involved by lymphoma. Differential cell analysis showed preferential lymphocyte labelling. The classification and management of the disease were changed accordingly. Our findings suggest that a future role for99mTc-HMPAO labelled white cells in the assessment of disease activity of lymphoma should be investigated.</div></front></TEI><mods xsi:schemaLocation="http://www.loc.gov/mods/v3 file:///applis/istex/home/loadistex/home/etc/xsd/mods.xsd" version="3.4" istexId="c337100ca31f723f70c7d6b431d528df446d7e0d"><titleInfo lang="eng"><title>Uptake of technetium-99m hexamethylpropylene amine oxime labelled white cells in lymph nodes involved in non-Hodgkin's lymphoma</title></titleInfo><name type="personal"><namePart type="given">Adil M.</namePart><namePart type="family">AL-Nahhas</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK</affiliation></name><name type="personal"><namePart type="given">Pantelis</namePart><namePart type="family">Hjiyiannakis</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Clinical Oncology, The Royal Marsden Hospital, Surrey, UK</affiliation></name><name type="personal"><namePart type="given">Peter A. G.</namePart><namePart type="family">Hammersley</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK</affiliation></name><name type="personal"><namePart type="given">V. Ralph</namePart><namePart type="family">McCready</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Nuclear Medicine, The Royal Marsden Hospital, Surrey, UK</affiliation></name><name type="personal"><namePart type="given">Alan H.</namePart><namePart type="family">Horwich</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Clinical Oncology, The Royal Marsden Hospital, Surrey, UK</affiliation></name><typeOfResource>text</typeOfResource><genre>Case report</genre><genre>Original Paper</genre><originInfo><publisher>Springer-Verlag, Berlin/Heidelberg</publisher><dateCreated encoding="w3cdtf">1995-07-13</dateCreated><dateValid encoding="w3cdtf">2005-05-12</dateValid><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="eng">Radiolabelled white cell scanning is widely used to detect the presence of infection. We present a case of non-Hodgkin's lymphoma manifesting with signs and symptoms suggestive of infection, in which a technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) white cell scan demonstrated high uptake in lymph nodes involved by lymphoma. Differential cell analysis showed preferential lymphocyte labelling. The classification and management of the disease were changed accordingly. Our findings suggest that a future role for99mTc-HMPAO labelled white cells in the assessment of disease activity of lymphoma should be investigated.</abstract><subject lang="eng"><genre>Key words</genre><topic>Lymphoma</topic><topic>Technetium-99m hexamethylpropylene amine oxime</topic><topic>White blood cell labelling</topic><topic>Indium-111</topic></subject><relatedItem type="series"><titleInfo type="abbreviated"><title>Eur J Nucl Med</title></titleInfo><titleInfo><title>European Journal of Nuclear Medicine</title><partNumber>Year: 1995</partNumber><partNumber>Volume: 22</partNumber><partNumber>Number: 12</partNumber></titleInfo><genre>Archive Journal</genre><originInfo><dateIssued encoding="w3cdtf">1995-12-01</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><subject usage="primary"><topic>Medicine & Public Health</topic><topic>Imaging / Radiology</topic><topic>Nuclear Medicine</topic></subject><identifier type="issn">0340-6997</identifier><identifier type="issn">Electronic: 1619-7089</identifier><identifier type="matrixNumber">259</identifier><identifier type="local">IssueArticleCount: 20</identifier><recordInfo><recordOrigin>Springer-Verlag, 1995</recordOrigin></recordInfo></relatedItem><identifier type="doi">10.1007/BF01791154</identifier><identifier type="matrixNumber">Art14</identifier><identifier type="local">BF01791154</identifier><accessCondition type="use and reproduction">MetadataGrant: OpenAccess</accessCondition><accessCondition type="use and reproduction">AbstractGrant: OpenAccess</accessCondition><accessCondition type="restriction on access">BodyPDFGrant: Restricted</accessCondition><accessCondition type="restriction on access">BodyHTMLGrant: Restricted</accessCondition><accessCondition type="restriction on access">BibliographyGrant: Restricted</accessCondition><accessCondition type="restriction on access">ESMGrant: Restricted</accessCondition><part><extent unit="pages"><start>1453</start><end>1456</end></extent></part><recordInfo><recordOrigin>Springer-Verlag, 1995</recordOrigin><recordIdentifier>259_1995_Article_BF01791154.pdf</recordIdentifier></recordInfo></mods></record>Pour manipuler ce document sous Unix (Dilib)
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